{"product_id":"affinitydna-dog-mdr1-dna-test-kit-home-cheek-swab-test-for-one-dog","title":"AffinityDNA Dog MDR1 DNA Test Kit, Home Cheek Swab Test for One Dog","description":"\u003cp\u003e\u003cstrong\u003eAffinityDNA Dog MDR1 DNA Test Kit checks a dog of any breed for the ABCB1 mutation linked to drug sensitivity, using four cheek swabs for one dog and reporting results by email in 10–15 working days after sample receipt.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eReports Clear, Carrier or Affected — shows which of the three MDR1 genotypes your dog has.\u003c\/li\u003e\n\u003cli\u003eFour sterile cheek swabs for one dog — collect a home DNA sample without a blood draw.\u003c\/li\u003e\n\u003cli\u003eWorks for all dog breeds — test a puppy or adult dog for the MDR1 mutation.\u003c\/li\u003e\n\u003cli\u003eInstructions, registration form and return envelope included — the kit provides the listed sample-collection materials.\u003c\/li\u003e\n\u003cli\u003eResults by email in 10–15 working days after the laboratory receives the sample — know when to expect the report.\u003c\/li\u003e\n\u003cli\u003eComplete test kit with no extra fees — supports straightforward test registration and sample return.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMDR1 testing is useful when you want genetic information to discuss with your veterinarian or when making breeding decisions. The result can help breeders avoid producing MDR1 carrier or affected offspring and reduce the mutation’s frequency in future generations. This is a health test, not a breed test.\u003c\/p\u003e\n\u003ch3\u003eWhat does the AffinityDNA Dog MDR1 DNA Test Kit tell me?\u003c\/h3\u003e\n\u003cp\u003eIt identifies whether the tested dog has inherited the mutated ABCB1 gene and assigns one of three genotypes: Clear, Carrier or Affected. MDR1 is inherited as an autosomal incomplete dominant trait, so a dog with one mutation copy is at increased risk of sensitivity to certain drugs; two copies can mean a higher risk of adverse reactions.\u003c\/p\u003e\n\u003cp\u003eThe mutation can interfere with p-glycoprotein, a protein that helps pump certain drugs and toxins out of the body. When its function is limited, higher levels of some drugs may enter the brain.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eClear: two mutation-free copies; the dog is not affected by MDR1.\u003c\/li\u003e\n\u003cli\u003eCarrier: one normal copy and one mutation; increased risk of drug sensitivity.\u003c\/li\u003e\n\u003cli\u003eAffected: two mutated copies; at risk of adverse drug reactions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow do I collect a sample, and what is in the kit?\u003c\/h3\u003e\n\u003cp\u003eCollect the dog’s DNA using the supplied sterile cheek swabs and follow the step-by-step instructions. All four swabs are intended for one dog; the kit also contains a registration form and return envelope.\u003c\/p\u003e\n\u003cp\u003eAfter the laboratory receives the sample, results are sent by email in 10–15 working days. AffinityDNA has more than 15 years of experience in DNA testing and established partnerships with highly accredited DNA testing laboratories.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHome cheek-swab sample collection.\u003c\/li\u003e\n\u003cli\u003eFour swabs for testing one dog.\u003c\/li\u003e\n\u003cli\u003eRegistration and sample-return materials included.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow can MDR1 results help with medication and breeding decisions?\u003c\/h3\u003e\n\u003cp\u003eThe test is designed as a convenient, accurate and affordable tool to help identify dogs with the MDR1 mutation. Dogs with one or two copies may be at risk of neurologic symptoms from certain common drugs, and reactions in dogs with two copies can include excess salivation, tremors, anorexia, blindness and possibly death.\u003c\/p\u003e\n\u003cp\u003eShare a Carrier or Affected result with your veterinarian so they can consider dosage adjustments or alternative medication. Breeders can use the genetic result to help avoid producing carrier and affected offspring; the test does not identify a dog’s breed.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFor all breeds of dog.\u003c\/li\u003e\n\u003cli\u003eUseful for veterinary medication discussions and breeding decisions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis kit suits dog owners seeking an MDR1 result for a puppy or adult, and breeders making informed genetic decisions. It provides a home cheek-swab test for one dog, with Clear, Carrier or Affected results delivered by email.\u003c\/p\u003e\n\u003csection class=\"product-faq-snippet\"\u003e\u003ch3\u003eFAQ\u003c\/h3\u003e\n\u003cdiv class=\"faq-item\"\u003e\n\u003cp class=\"faq-q\"\u003eQ: What results does the AffinityDNA Dog MDR1 DNA Test Kit provide?\u003c\/p\u003e\n\u003cp class=\"faq-a\"\u003eA: The AffinityDNA Dog MDR1 DNA Test Kit reports one of three genotypes: Clear, Carrier or Affected, based on whether the dog has inherited the ABCB1 mutation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"faq-item\"\u003e\n\u003cp class=\"faq-q\"\u003eQ: What comes with the AffinityDNA Dog MDR1 DNA Test Kit?\u003c\/p\u003e\n\u003cp class=\"faq-a\"\u003eA: The AffinityDNA Dog MDR1 DNA Test Kit includes four sterile cheek swabs for one dog, step-by-step collection instructions, a registration form and a return envelope.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/section\u003e","brand":"AffinityDNA","offers":[{"title":"Default Title","offer_id":55680973472087,"sku":"B0857HM8KD","price":107.95,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1056\/4780\/0663\/files\/affinitydna-dog-mdr1-test-kit-front.jpg?v=1793440006","url":"https:\/\/bathpetsupplies.co.uk\/products\/affinitydna-dog-mdr1-dna-test-kit-home-cheek-swab-test-for-one-dog","provider":"BathPetSupplies","version":"1.0","type":"link"}